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Search for Thrombocytopenia in General Medicine
Physician-authored summaries on the latest research on thrombocytopenia, editorials on thrombocytopenia, and perspectives on thrombocytopenia - drawn from the top medical journals.
You searched for: thrombocytopenia Items 1 to 20 of 43 results
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A New Investigational Drug for Treatment of Thrombocytopenia
- December 27, 2007
- Allan S. Brett, MD
In two trials, eltrombopag showed promise as thrombocytopenia treatment.- Covering:
- Bussel JB et al., N Engl J Med 2007 Nov 29; 357:2237.
- McHutchison JG et al., N Engl J Med 2007 Nov 29; 357:2227.
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Heparin-Induced Thrombocytopenia as a Cause of Thromboembolism in Outpatients
- March 8, 2002
- Richard Saitz, MD, MPH
The diagnosis of heparin-induced thrombocytopenia usually is considered when platelet counts drop during the first 2 weeks of heparin therapy. Investigators now report on a . . .- Covering:
- Rice L et al., Ann Intern Med 2002 Feb 5; 136:210-15.
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Time Course of Heparin-Induced Thrombocytopenia
- May 4, 2001
- AS Brett
Some heparin recipients develop thrombocytopenia, which is caused by IgG antibodies against complexes of platelet factor 4 and heparin. These Canadian researchers describe the time . . .- Covering:
- Warkentin TE and Kelton JG., N Engl J Med 2001 Apr 26; 344:
1286 1292 .
- Warkentin TE and Kelton JG., N Engl J Med 2001 Apr 26; 344:
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NO THROMBOCYTOPENIA WITH LOW-MOLECULAR-WEIGHT HEPARIN.
- May 23, 1995
- AS Brett
Heparin-induced thrombocytopenia paradoxically predisposes patients to thrombotic complications. To assess the frequency of this problem, Canadian researchers followed daily platelet counts in 665 patients who . . .- Covering:
- Warkentin TE, et al., N Engl J Med 1995 May 18; 332:
1330 1335 .
- Warkentin TE, et al., N Engl J Med 1995 May 18; 332:
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SPLENIC IRRADIATION FOR IMMUNE THROMBOCYTOPENIA.
- June 30, 1992
- ASB
First-line treatment for immune thrombocytopenia includes corticosteroids, splenectomy, or both. However, each of these therapies carries risks that are particularly problematic in elderly or chronically . . .- Covering:
- Calverly DC et al., Ann Intern Med 1992 Jun 15; 116:
977 981 .
- Calverly DC et al., Ann Intern Med 1992 Jun 15; 116:
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It's Confirmed: Vancomycin Causes Immune Thrombocytopenia
- March 13, 2007
- Abigail Zuger, MD
Serious clinical sequelae may result. CME Exam- Covering:
- Von Drygalski A et al., N Engl J Med 2007 Mar 1; 356:904-10.
- Warkentin TE., N Engl J Med 2007 Mar 1; 356:891-3.
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Autologous Cryopreserved Platelets for Treating Thrombocytopenia
- August 6, 2002
- Sir Brian Jarman, PhD, FRCP, FRCGP, FFPHM, FMedSci
During the past 20 years, platelet transfusions have been used increasingly in patients who undergo intensive myelosuppressive therapy. Due to concerns about alloimmunization-related risks, attempts . . .- Covering:
- Vadhan-Raj S et al., Lancet 2002 Jun 22; 359:2145-52.
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Rituximab for Idiopathic Thrombocytopenic Purpura?
- March 8, 2007
- Deborah M. DeMarco, MD
In the absence of randomized, controlled trials, clinicians should be very cautious about using rituximab for this or any other autoimmune condition.- Covering:
- Arnold DM et al., Ann Intern Med 2007 Jan 2; 146:25-33.
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Romiplostim: A New Approach for ITP?
- February 26, 2008
- Bruce Soloway, MD
A therapeutic protein that raises platelet counts, rather than prevents platelet destruction, could hold promise in treating this autoimmune disorder.- Covering:
- Kuter DJ et al., Lancet 2008 Feb 2; 371:395.
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ZIDOVUDINE FOR HIV-RELATED THROMBOCYTOPENIA.
- March 21, 1989
- ASB
Immune thrombocytopenic purpura is a well-recognized complication of human immunodeficiency virus (HIV) infection, although the exact mechanism of platelet destruction is unknown. These researchers postulated . . .- Covering:
- Oksenhendler E et al., Ann Intern Med 1989 Mar; 110:
365 368 .
- Oksenhendler E et al., Ann Intern Med 1989 Mar; 110:
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A Surprising Risk for Ticlopidine.
- April 14, 1998
- R Saitz
Ticlopidine, gaining popularity for stroke prevention and after cardiac stenting, has serious side effects, including neutropenia, thrombocytopenia, and cholestasis. This report identifies a new complication, . . .- Covering:
- Bennett CL et al., Ann Intern Med 1998 Apr 1; 128:
541 544 .
- Bennett CL et al., Ann Intern Med 1998 Apr 1; 128:
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PROPHYLACTIC PLATELET TRANSFUSIONS FOR ACUTE LEUKEMIA.
- December 3, 1991
- ASB
Patients being treated for acute leukemia are frequently given prophylactic platelet transfusions when severe thrombocytopenia occurs. However, the threshold for such transfusions is controversial.- Covering:
- Gmur J et al., Lancet 1991 Nov 16; 338:
1223 1226 .
- Gmur J et al., Lancet 1991 Nov 16; 338:
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ENDOTOXEMIA AS AN EARLY SIGN OF SEPTICEMIA.
- April 8, 1988
- HGA
The diagnosis of septicemia (fever plus shock, oliguria, thrombocytopenia or metabolic acidosis) is usually made by establishing the presence of bacteremia by positive blood cultures; . . .- Covering:
- van Deventer S J H; Buller H R; ten Cate J W; Sturk A; Pauw W., Lancet 1988 Mar 19; 1:
605 609 .
- van Deventer S J H; Buller H R; ten Cate J W; Sturk A; Pauw W., Lancet 1988 Mar 19; 1:
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Long-Term Clinical and Immunological Effects of Anti-CD20 Treatment in Refractory SLE
- June 24, 2008
- Deborah M. DeMarco, MD
Anti-CD20 treatment could be beneficial for treatment of patients with refractory lupus nephritis and autoimmune cytopenias.- Covering:
- Lindholm C et al., J Rheumatol 2008 May; 35:826.
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Myelodysplastic Syndromes: Incidence and Survival
- April 26, 2007
- Allan S. Brett, MD
Data from a U.S. cancer surveillance program indicate an incidence of about 3.5 cases per 100,000 per year.- Covering:
- Ma X et al., Cancer 2007 Apr 15; 109:1536-42.
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A Noninvasive Way to Identify Esophageal Varices?
- December 13, 2006
- Allan S. Brett, MD
Patients at low risk had high ratios of platelet count to bipolar spleen diameter.- Covering:
- Giannini EG et al., Am J Gastroenterol 2006 Nov; 101:2511-9.
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Safety and Efficacy of LMW Heparin in Older or Obese Patients
- March 11, 2005
- Jamaluddin Moloo, MD, MPH
Fixed-dose, low-molecular-weight (LMW) heparins are used routinely to prevent venous thromboembolism (VTE). However, such regimens could be less effective in obese patients and could be . . .- Covering:
- Kucher N et al., Arch Intern Med 2005 Feb 14; 165:341-5.
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Risk for Intracranial Hemorrhage Among Warfarin Users with Atrial Fibrillation
- December 21, 2004
- Richard Saitz, MD, MPH, FACP, FASAM
Which INR levels and patient characteristics are most likely to confer risk?- Covering:
- Fang MC et al., Ann Intern Med 2004 Nov 16; 141:745-52.
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Gaucher Disease Usually Does Not Complicate Pregnancy
- March 30, 2004
- Robert W. Rebar, MD
As the most common glycolipid storage disorder, Gaucher disease does turn up in women of reproductive age. How do affected women fare in pregnancy? Researchers . . .- Covering:
- Elstein Y et al., Am J Obstet Gynecol 2004 Feb; 190:435-41.
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THE SARS EPIDEMIC
- December 31, 2003
No sooner did bioterrorism fade from the headlines last year than an infectious-disease natural catastrophe took its place. At last count, more than 8000 people . . .
You searched for: thrombocytopenia Items 1 to 20 of 43 results
