Another Flawed HIV Vaccine Disappoints
SUMMARY AND COMMENT
November 12, 2009
Abigail Zuger, MD
But this time, experts salvage a hopeful message.
Reviewing:
Rerks-Ngarm S et al., N Engl J Med 2009 Oct 20
Dolin R., N Engl J Med 2009 Oct 20
Price of Nonadherence to Antihypertensive Medications
SUMMARY AND COMMENT
High adherers had a significantly lower risk for cardiovascular disease.
Reviewing:
Mazzaglia G et al., Circulation 2009 Oct 20; 120:1598
Chobanian AV., Circulation 2009 Oct 20; 120:1558
Case Management for Depression in Primary Care
SUMMARY AND COMMENT
Specially trained healthcare assistants effectively managed depressed patients in a German study.
Reviewing:
Gensichen J et al., Ann Intern Med 2009 Sep 15; 151:369
Dietrich AJ., Ann Intern Med 2009 Sep 15; 151:425
Cervical Collar, Physical Therapy, or "Wait and See" for Recent-Onset Cervical Radiculopathy?
SUMMARY AND COMMENT
Pain scores were significantly lower in the collar and physical therapy groups.
Reviewing:
Kuijper B et al., BMJ 2009 Oct 7; 339:b3883
Anticholinergic Drugs and Acute Urinary Retention
SUMMARY AND COMMENT
November 10, 2009
Allan S. Brett, MD
Risk is highest during the first several weeks of treatment.
Reviewing:
Martín-Merino E et al., J Urol 2009 Oct; 182:1442
Glucose Control in Type 2 Diabetes: Review of Cardiovascular Outcomes
SUMMARY AND COMMENT
Intensive control led to fewer nonfatal MIs but no change in 5-year all-cause mortality.
Reviewing:
Kelly TN et al., Ann Intern Med 2009 Sep 15; 151:394
Long-Acting Bronchodilators With or Without Inhaled Steroids in COPD
SUMMARY AND COMMENT
Risk for moderate COPD exacerbations, but not severe exacerbations, was lower with combined therapy.
Reviewing:
Rodrigo GJ et al., Chest 2009 Oct; 136:1029
Cruise Ship Restrooms: An Exposé
SUMMARY AND COMMENT
November 5, 2009
Abigail Zuger, MD
Some are very clean, but most are not . . . until an outbreak of gastroenteritis occurs.
CME
Reviewing:
Carling PC et al., Clin Infect Dis 2009 Nov 1; 49:1312
Multifocal Glasses and Risk for Falling
SUMMARY AND COMMENT
Ground-level obstacles can be precarious with these glasses.
Reviewing:
Menant JC et al., J Am Geriatr Soc 2009 Oct; 57:1833
Comparison of Three Insulin Regimens
SUMMARY AND COMMENT
Adding once-daily basal insulin to oral therapy conferred some advantages over alternate regimens.
CME
Reviewing:
Holman RR et al., N Engl J Med 2009 Oct 29; 361:1736
Roden M., N Engl J Med 2009 Oct 29; 361:1801