Gabapentin–Nortriptyline Combination Therapy for Neuropathic Pain
SUMMARY AND COMMENT
October 27, 2009
Bruce Soloway, MD
Pain intensity was lower with combination therapy than with either monotherapy.
Reviewing:
Gilron I et al., Lancet 2009 Oct 10; 374:1252
Glucocorticoid Use Is Associated with Risk for Atrial Fibrillation
SUMMARY AND COMMENT
A large case-control study suggests that glucocorticoid use is linked to AF.
Reviewing:
Christiansen CF et al., Arch Intern Med 2009 Oct 12; 169:1677
Trends in Hip Fracture Incidence and Mortality — 1986–2005
SUMMARY AND COMMENT
Incidence peaked in 1995, and then declined; mortality was down overall.
Reviewing:
Brauer CA et al., JAMA 2009 Oct 14; 302:1573
Midlife Overweight and Obesity Predict Lower Chance for Healthy Survival After Age 70
SUMMARY AND COMMENT
For every unit of BMI >25 kg/m2 at midlife, odds for disease-free survival at age 70 decreased by 12%.
Reviewing:
Sun Q et al., BMJ 2009 Sep 29; 339:b3796
Hormone Therapy Is Associated with Excess Lung Cancer Mortality in WHI Participants
SUMMARY AND COMMENT
October 27, 2009
Bruce Soloway, MD
NSCLCs were more aggressive in hormone recipients.
Reviewing:
Chlebowski RT et al., Lancet 2009 Oct 10; 374:1243
New Retrovirus Is Associated with Chronic Fatigue Syndrome
SUMMARY AND COMMENT
Could a human retrovirus be one cause of CFS?
CME
Reviewing:
Lombardi VC et al., Science 2009 Oct 8
Effect of Weight Loss on Obstructive Sleep Apnea in People with Type 2 Diabetes
SUMMARY AND COMMENT
Losing 25 lbs resulted in significantly fewer OSA events in obese patients.
Reviewing:
Foster GD et al., Arch Intern Med 2009 Sep 28; 169:1619
Small Thigh Circumference Is Associated with Cardiovascular Morbidity and Premature Death
SUMMARY AND COMMENT
Small thighs might be an easily identifiable marker for cardiovascular risk.
Reviewing:
Heitmann BL and Frederiksen P., BMJ 2009 Sep 3; 339:b3292
Gastric Bypass vs. Banding — A Randomized Trial
SUMMARY AND COMMENT
Bypass led to greater weight loss but was associated with more complications.
Reviewing:
Nguyen NT et al., Ann Surg 2009 Oct; 250:631
Treatment of Localized Prostate Cancer in the Era of PSA Screening
SUMMARY AND COMMENT
Watchful waiting is appropriate in older men with localized cancers.
Interview
Reviewing:
Lu-Yao GL et al., JAMA 2009 Sep 16; 302:1202