From the publishers of The New England Journal of Medicine

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General Medicine Top Stories of 2009: Most Read

FEATURE

How Much Evidence Do We Need to Change Practices in Which We Firmly Believe?

Enough already! Randomized trials show that tight glucose control in patients with long-standing type 2 diabetes isn't beneficial.

SUMMARY AND COMMENT

Validation of a Single-Question Alcohol Screening Test

One short simple question effectively identified patients with unhealthy alcohol use.

SUMMARY AND COMMENT

BP-Lowering Drugs and Prevention of Cardiovascular Disease

All five classes of BP-lowering drugs were effective, regardless of patients’ histories.

SUMMARY AND COMMENT

Vitamin D Levels in Elders

Most older people had low serum levels, and at least 25% of elders had frank vitamin D deficiency.

SUMMARY AND COMMENT

New Position Papers on Type 2 Diabetes Management

One document offers a sensible treatment algorithm; the other offers perspective on the relation between glycemic control and macrovascular complications.

NEWS IN CONTEXT

New Human Illness from Swine Flu Virus

Certain features suggest the risk for a pandemic.

SUMMARY AND COMMENT

Statins for Primary Prevention of Cardiovascular Disease

Statin users were less likely to experience major adverse coronary or cerebrovascular events.

SUMMARY AND COMMENT

Is 140/90 Low Enough for Nondiabetic Hypertensive Patients?

A study supports a more aggressive approach to BP reduction.

SUMMARY AND COMMENT

Poor Prognosis Among Community Dwellers with Mild Hyponatremia

In middle-aged or older adults, mild hyponatremia predicted death and MI.

SUMMARY AND COMMENT

Two Surprising Theories About Hypertension

Mouse models for hypertension suggest new pathways.

 

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